【佳学基因检测】不孕不育与生殖缺陷专家:张爱军教授
遗传病、罕见病基因检测导读:
张爱军,教授, 国际著名生殖专家。擅长卵母细胞浆内单精子注射、体外受精-胚胎移植、胚胎活检、胚胎冷冻、自存精子冷冻等各项辅助生殖技术实验室技术。现任上海交通大学附属瑞金医院妇产科学博士生导师。
张爱军教授简介:
张爱军,生殖医学中心实验室主任,副主任技师,1998年毕业于山东大学生命科学院细胞及分子生物学专业。从事人类辅助生殖技术实验室工作至今,掌握胚胎学、生殖医学、遗传学等专业理论知识,熟练卵母细胞浆内单精子注射、体外受精-胚胎移植、胚胎活检、胚胎冷冻、自存精子冷冻等各项辅助生殖技术实验室技术。作为主要技术骨干,早期参与了瑞金医院生殖医学中心的设计和筹建;中心建成之后,认真完成实验室各项质控工作,同时培训相关技术人员,为顺利开展临床工作奠定了良好的基础。在迎接卫生部专家的评审与复评审工作中,尽职尽责,使生殖医学中心顺利通过卫生部的检查,获得开展人类辅助生殖技术的资质做出了突出贡献。工作中建立了系统有效的实验室质控程序和严格的胚胎发育潜能评估系统,取得了良好的临床效果。平时积极配合临床,开展新技术、新项目,不断丰富临床诊断资料,其中改良机械法辅助孵化透明带切口方式改善卵母细胞浆内单精子注射方式的研究,作为新技术分别在中华医学成立大会和亚洲男科学大会上交流。曾先后到新加坡国立大学和香港中文大学生殖中心参观学习。作为课题负责人,目前承担上海市科委自然基金课题1项;作为主要研究人员,参与国家自然基金和上海市科委重大课题各1项,近3年在国家核心期刊发表相关学术论文10余篇。曾获2004年度瑞金医院先进员工奖。
张爱军教授究方向
人类种植前胚胎发育潜能及子宫内膜容受性
张爱军教授社会任职
张爱军教授在国际生殖领域的研究领域:
张爱军教授对国际生殖领域及出生缺陷的贡献
- Huihui Xu, Mingjuan Zhou, Yi Cao, Dan Zhang, Mi Han, Xinxing Gao, Bufang Xu, Aijun Zhang (通讯作者) Genome-wide analysis of long noncoding RNAs, microRNAs, and mRNAs forming a competing endogenous RNA network in repeated implantation failure Gene 2019 /
- Dan Zhang, Lan Xia, Huihui Xu, Qian Chen, Bailing Jin, Aijun Zhang* and Bufang Xu* (通讯作者) Flexible Low-Dose GnRH Antagonist Protocol Is Effective in Patients With Sufficient Ovarian Reserve in IVF Frontiers in Endocrinology 2019 9:767-7
- Xiaoyu Xia#, Xiaowei Zhou#, Yanmei Quan#, Yanqin Hu, Fengying Xing, Zhengzheng Li, Bufang Xu*, Chen Xu* and Aijun Zhang* Germline deletion of Cdyl causes teratozoospermia and progressive infertility in male mice Cell Death and Disease 2019 10:229-13
- Wen-Jie Zhou, Jie Zhang, Hui-Li Yang, Ke Wu, Feng Xie, Jiang-Nan Wu, Yan Wang, Li Yao, Yan Zhuang,Jiang-Dong Xiang, Ai-Jun Zhang* (通讯作者), Yin-Yan He* and Ming-Qing Li* Estrogen inhibits autophagy and promotes growth of endometrial cancer by promoting glutamine metabolism Cell Communication and Signaling 2019 17:99-15
- Jin Bailing, Niu Zhihong, Xu Bufang, Chen Qian, Zhang Aijun (通讯作者) comparison of clinical outcomes among dual ovarian stimulation, mild stimulation and luteal phase stimulation protocols in women with poor ovarian response Gynecol Endocrinol 2018 34(8) :694-697
- F Guo, C Si, M Zhou, J Wang, D Zhang, Leung PCK, B Xu,Zhang A (通讯作者) Decreased PECAM1-mediated TGF-β1 expression in the mid-secretory endometrium in women with recurrent implantation failure 《Human Reproduction》 2018 33 (5) :832-843
- B Xu, M Zhou, J Wang, D Zhang, F Guo, Si C, Leung PCK, Zhang A (通讯作者) Increased AIF-1-mediated TNF-α expression during implantation phase in IVF cycles with GnRH antagonist protocol 《Human Reproduction》 2018 33 (7):1270-1280
- Bufang Xu1,*, Jingwen Wang1,*, Lan Xia1, Dan Zhang1 (通讯作者), Xian Wu1 & Aijun Zhang1,2 GnRH antagonist negatively affects endometrial receptivity in in vitro fertilization (IVF) cycles, however, its underlying mechanism remains unclear. 《Scientific Reports》 2017 3(7):39912
- N.Zhihong,F.Yun,Z.Pinggui,Z.Sulian,Aijun Zhang (通讯作者) Cytokine profiling in the Eutopin Endometrium of Adenomyosis During the Implantation Window after Ovarian Stimulation Reproductive Sciences 2016 23(1):124-133
- 李雁,叶瑶,徐步芳,张爱军 (通讯作者) 抗神经生长隐私抗体用于改善子宫腺肌病小鼠宫腔内环境的研究 生殖与避孕 2015 35(6):353-358
- Qian Chen, Aijun Zhang (共同第一作者),Feng Yu,Jing Gao,Yue Liu,Chenli Yu,Xu Zhou,Chen Xu Label-Free Proteomics Uncovers Energy Metabolism and Focal Adhesion Regulations Responsive for Endometrium Receptivity proteome research 2015 14,1831-1842
- Bu-fang Xu,Guang-yan Wang,Wei-min Fan,Qian Chen, Ai-jun Zhang (通讯作者) Which is the Best Protocol of Ovarian Stimulation Prior to Artificial Insemination by Donor Sperm. Journal of Reproduction & Contraception Journal of Reproduction & Contraception 2014 25(1):41-48
- Ling Wu, Bufang Xu, Weimin Fan, Xiaobin Zhu, Guangyan Wang, Aijun zhang (通讯作者), Adiponectin protects Leydig cells against pro-inflammatory cytokines by suppressing the nuclear factor-kappaB signaling pathway FEBS Journal 2013 280(16):3920-7
- Wu L, Zhang A, Sun Y, Zhu X, Fan W, Lu X, Yang Q, Feng Y Sirt1 exerts anti-inflammatory effects and promotes steroidogenesis in Leydig cells Fertil Steril 2012 98(1):194-9
- Aijun Zhang, Bufang Xu, Yijuan Sun, Xiaowei Lu, Ruihuan Gu, Qian Chen, Yun Feng, Chen Xu The effect of human cumulus cells on the maturation and developmental potential of immature oocytes in ICSI cycles. J Assist Reprod Genet 2012 29:313-9
- 朱晓斌,冯云,吴玲,樊卫民,陆小溦,孙贻娟,谷瑞环,张爱军 (通讯作者) 自精保存在辅助生殖技术中的意义 中国优生与遗传杂志 2012 20(3):118-9
- Bufang Xu, Xiaoxi Sun, Lu Li, Ling Wu, Aijun Zhang (通讯作者), Yun Feng Pinopodes, leukemia inhibitory factor, integrin-b3, and mucin-1 expression in the peri-implantation endometrium of women with unexplained recurrent pregnancy loss Fertil Steril 2012 98(2):389-95
- 朱晓斌,冯云,杨青青,陆小溦,樊卫民,吴铃,李志超,张爱军 (通讯作者) 染色体异常对IVF-ET妊娠结局的影响 中国男科学杂志 2012 26(10):29-32
- Sun Y, Feng Y, Zhang A, Lu X, Niu Z, Gu R Frozen-thawed embryo transfer cycles in China: clinical outcomes of two and three multicellular embryos transfers J Assist Reprod Genet 2012 29(5):417-21
- Aijun Zhang, Bufang Xu, Yijuan Sun, Xiaowei Lu, Ruihuan Gu, Ling Wu, Yun Feng, Chen Xu Dynamic changes of histone H3 trimethylated at positions K4 and K27 in human oocytes and pre-implantation embryos Fertil Steril 2012 98(4):1009-16
- 徐步芳, 孙贻娟,陆小溦,朱晓斌,冯云,张爱军 (通讯作者) 精子DNA碎片率对常规体外受精-胚胎移植结局的影响 中国男科学杂志 2011 25(8):23-26
- 谷瑞环,孙贻娟,陆小溦,冯云,张爱军 (通讯作者) 第二极体排出时间在预测体外受精结局中的价值 中华临床医师杂志 2011 5(14):4127-32
- 徐步芳,冯云,王枫钊,牛志宏,陈骞,张爱军 (通讯作者) 胚胎移植日子宫内膜运动波对冻融胚胎移植周期妊娠结局的预测价值 中华临床医师杂志 2011 5(14):32-5
- 朱晓斌, 冯云, 纪冬梅, 刘建兵, 徐步芳, 张爱军 (通讯作者) Y染色体微缺失检测及生激素水平研究在非梗阻性无精子症患者睾丸穿刺中的意义 中国男科学杂志 2010 24(2):35-38
- 纪冬梅, 冯云, 李铮, 朱晓斌, 张爱军 (通讯作者) 810例严重少(无)精子症患者Y染色体微缺失筛查与分析 中国优生与遗传杂志 2010 18(2):36-38
- Qian CHEN, Ai-jun ZHANG (通讯作者), Yun FENG, Xiao-wei LU, Dong-mei JI, Zhi-peng XU Effect of the P1 Medium and the ECM Medium on Embryo Journal of Reproduction & Contraception 2009 20(2):22-7
- 孙贻娟,张爱军 (通讯作者),冯 云, 张慧琴,牛志宏,陆小溦 不同胚胎选择体系对体外受精-胚胎移植妊娠结局的影响 生 殖 与 避 孕 2009 29(1):26-30
- Niu Z, Feng Y, Zhang A, Sun Y, Zhang H Progesterone levels on oocyte retrieval day can predict the quantity of viable embryos but not pregnancy outcome of intracytoplasmic sperm injection Gynecol Endocrinol 2008 24(8):452-8
- 李雁, 冯云, 孙贻娟, 牛志宏, 张爱军 (通讯作者) 人卵母细胞与体细胞的电融合效率 上海交通大学学报( 医学版) 2007 27:837-840 本文的目的只是起传播知识的目的,不代表本网站完全认同本文的观点,不暗示或者说明文中内容与人物与佳学基因存在任何关系。