【佳学基因检测】癌症研究中的磁共振成像

肿瘤基因检测权威机构如何判断

挖掘基因检测人员学科学习手册听到《Eur J Cancer》在. 2002 Nov;38(16):2147-56.发表了一篇题目为《癌症研究中的磁共振成像》肿瘤靶向药物治疗基因检测临床研究文章。该研究由B D Ross , T L Chenevert, A Rehemtulla等完成。促进了肿瘤的精准治疗与个性化用药的发展，进一步强调了基因信息检测与分析的重要性。

肿瘤临床大数据研究内容关键词：

治疗评估,抗肿瘤反应,生物发光成像,磁共振

肿瘤靶向治疗基因检测临床应用结果

抗肿瘤反应的非侵入性评估以及体内转基因表达的位置、幅度和持续时间的相关性对于评估癌症基因治疗方案特别有用。本综述介绍了磁共振 (MR) 如何用于通过无创定量细胞杀伤来评估治疗效果、在肿瘤体积变化之前检测治疗反应以及检测肿瘤反应的空间异质性和定量转基因表达。此外，还介绍了使用生物发光成像 (BLI) 评估治疗效果和体内转基因表达的应用。这些例子提供了动物肿瘤模型成像有助于改进实验治疗剂评估的领域的概述。

肿瘤发生与复发转移国际数据库描述：

Non-invasive assessment of antineoplastic response and correlation of the location, magnitude and duration of transgene expression in vivo would be particularly useful for evaluating cancer gene therapy protocols. This review presents selected examples of how magnetic resonance (MR) has been used to assess therapeutic efficacy by non-invasive quantitation of cell kill, to detect a therapeutic response prior to a change in tumour volume and to detect spatial heterogeneity of the tumour response and quantitate transgene expression. In addition, applications of the use of bioluminescence imaging (BLI) for the evaluation of treatment efficacy and in vivo transgene expression are also presented. These examples provide an overview of areas in which imaging of animal tumour models can contribute towards improving the evaluation of experimental therapeutic agents.