【佳学基因检测】精神疾病基因检测指导基因治疗

品牌基因检测价格表还有吗

比较精神科的基因组学特征与治疗方案设计做了备注， 《World Neurosurg》在2013 Sep-Oct;80(3-4):S32.e11-8发表了一篇题目为《精神疾病的基因治疗》的通过基因编辑治疗精神疾病的临床应用前景研究文章。该研究由Yaroslav Gelfand, Michael G Kaplitt等完成。探讨了精神疾病的基因编辑及其矫正治疗方法， 这是一种基因检测得到可信结果后，对疾病的治疗的闭环方案，是基因信息在精准治疗上的以效果为评价标准的应用。

精神科神经科致病基因及精准治疗临床研究内容关键词：

精神科,基因治疗，沮丧，下边缘区，强迫症，小干扰RNA

神经科用药指导基因检测临床应用结果

随着帕金森病、阿尔茨海默病和儿科遗传疾病的大量临床试验的完成，基因治疗已成为临床神经外科领域的热门话题。随着对介导各种精神疾病的功能失调电路的理解不断加深，针对难治性精神疾病的深部脑刺激正在越来越多地在人类患者中进行探索。这些因素可能会促进精神疾病基因疗法的发展。由于基因治疗药物的递送需要与目前用于深部脑刺激的相同手术技术，神经外科医生可能会引领这一领域的发展，正如在神经系统疾病临床基因治疗的其他领域所发生的那样。佳学基因解码回顾了精神疾病基因治疗的现状，并特别关注可能转化为抑郁症、药物成瘾、强迫症和精神分裂症的人体试验的有前景的研究的特定领域。还讨论了精神科基因治疗相对独特的问题。关键词：5-HT； 5-羟色胺；AAV；瘾;腺相关病毒； 25区； BDNF;脑源性神经营养因子；中枢神经系统；消费者保护计划；中枢神经系统;条件性位置偏好；DISC1，沮丧;精神分裂症； FST；强制游泳测试；基因治疗;下边缘皮层； KO;昏死; NAcc;伏隔核;强迫症；强迫症; PD;帕金森综合症; SRF;血清反应因子；小干扰RNA；尖沙咀；尾部悬挂测试； p11; siRNA。

神经及精神疾病及其并发征、合并征国际数据库描述：

Gene therapy has become of increasing interest in clinical neurosurgery with the completion of numerous clinical trials for Parkinson disease, Alzheimer disease, and pediatric genetic disorders. With improved understanding of the dysfunctional circuitry mediating various psychiatric disorders, deep brain stimulation for refractory psychiatric diseases is being increasingly explored in human patients. These factors are likely to facilitate development of gene therapy for psychiatric diseases. Because delivery of gene therapy agents would require the same surgical techniques currently being employed for deep brain stimulation, neurosurgeons are likely to lead the development of this field, as has occurred in other areas of clinical gene therapy for neurologic disorders. We review the current state of gene therapy for psychiatric disorders and focus specifically on particular areas of promising research that may translate into human trials for depression, drug addiction, obsessive-compulsive disorder, and schizophrenia. Issues that are relatively unique to psychiatric gene therapy are also discussed.Keywords: 5-HT; 5-Hydroxytryptamine; AAV; Addiction; Adeno-associated virus; Area 25; BDNF; Brain-derived neurotrophic factor; CNS; CPP; Central nervous system; Conditioned place preference; DISC1; Depression; Disrupted In Schizophrenia-1; FST; Forced swim test; Gene therapy; Infralimbic cortex; KO; Knockout; NAcc; Nucleus accumbens; OCD; Obsessive-compulsive disorder; PD; Parkinson disease; SRF; Serum response factor; Small interfering RNA; TST; Tail suspension test; p11; siRNA.